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For a really different experience, look for unique Grand Canyon bus tours, such as a trip to the Hopi Mesas east of the Grand Canyon. The Hopi Indians live on their tribal lands the same way they have lived for thousands of years, and visitors can see their ancient pueblos first-hand on these tours.
The Hopi Cultural Center located on Second Mesa offers a hotel and restaurant, along with a cooperative art gallery showcasing Hopi artists and craftspeople. Prices are reasonable and the trip to the mesas is beautiful and haunting.
Some Grand Canyon bus tours offer tours to the mesas that originate in Las Vegas and include a visit to the South Rim. Many Hopi mesa tours originate in Sedona and Flagstaff, too.